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Archemix and SomaLogic Expand Strategic
Alliance
Broader relationship to advance aptamer technology
Cambridge,
MA and Boulder, CO
August 7, 2007
Archemix Corp. and SomaLogic, Inc. announced
today an expansion of their alliance focused on the use and development
of aptamers for therapeutic, diagnostic, and other applications.
This
expanded alliance broadens the companies’ existing
relationship by cross-licensing new technologies being developed
by the companies and sharing their respective know-how. Under the
terms of the expanded agreement, Archemix receives exclusive rights
to therapeutic uses of aptamers discovered by SomaLogic for a limited
number of targets identified by Archemix. Additionally, Archemix
will have the option of providing targets to SomaLogic for the
generation of aptamers. SomaLogic will receive rights to all ex
vivo uses of aptamers which it did not previously hold, including
the use of aptamers for affinity purification. Other provisions
of the original cross-license agreement between the two companies
remain unchanged. Financial terms were not disclosed.
About Aptamers
Aptamers are synthetically-derived oligonucleotides, or short
nucleic acid sequences. Aptamers represent an emerging class
of potential
therapeutic agents that Archemix believes may have broad application
to treat a variety of human diseases. Archemix believes that
aptamer therapeutics combine many of the beneficial characteristics
of biologics, small molecules and other classes of oligonucleotides,
such as antisense and small interfering RNA, or siRNA, without
exhibiting many of their disadvantages. Aptamers have the ability
to disrupt interactions between proteins, bind with high affinity
and specificity to their targets and can be designed to have
a specified duration of action.
About Archemix
Archemix is a biotechnology company focused on discovering, developing
and commercializing aptamer therapeutics. Using Archemix’s
proprietary processes for discovering aptamers, which are protected
by its patent portfolio, Archemix is developing aptamer product
candidates for cardiovascular and hematological diseases and
cancer. Archemix has completed a Phase 1 clinical trial for ARC1779,
its lead aptamer product candidate and, subject to regulatory
review of its proposed protocol, Archemix expects to commence
Phase 2a and Phase 1b clinical trials of ARC1779 in two distinct
indications in the fourth quarter of 2007. In addition, Archemix
has licensed its intellectual property to third parties to develop
their own aptamer product candidates. To date, Archemix has licensed
its intellectual property to discover or develop aptamer product
candidates to nine biotechnology and pharmaceutical companies,
including Pfizer, Merck Serono, Takeda Pharmaceuticals and Elan
Pharma. Archemix expects two of these aptamer product candidates
being developed by third parties to enter Phase 2 clinical trials
in the second half of 2007.
About SomaLogic
SomaLogic is developing proteomics systems and applications based
on its proprietary aptamer technology. The company's aptamer
arrays will allow researchers--and ultimately clinicians--to
measure large numbers of proteins simultaneously, providing
the foundation for new insights into disease and health. SomaLogic
is headquartered in Boulder, Colorado. Further information
about
the company can be found at www.somalogic.com.
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