< 2005 News Listings Senomyx, Inc. Announces Exercise of Over-Allotment and Closing of Public Offering of Common Stock FRESHNEWS.COM November 10, 2005 Senomyx, Inc. (NASDAQ:SNMX) (Company) today announced that Deutsche Bank Securities Inc. has exercised in full its over-allotment option to purchase 528,169 additional shares of common stock of the Company. The offering of 4,049,295 shares of common stock, including the over-allotment shares, closed on November 9, 2005, resulting in net proceeds to the Company of approximately $57.2 million. A prospectus supplement relating to the offering has been filed with the Securities and Exchange Commission (SEC) by the Company, and is available along with the related base prospectus filed with the SEC in connection with the shelf registration, on the SEC's website at www.sec.gov/. Deutsche Bank Securities Inc. is the sole underwriter for this offering. Printed copies of the prospectus supplement and the related base prospectus relating to the offering may also be obtained from Deutsche Bank Securities Inc., 60 Wall Street, 4th Floor, New York, NY 10005 (Tel: 212-250-2500). The common stock was offered in connection with a distribution by the issuer and represented a new financing. About Senomyx, Inc. (www.senomyx.com) Senomyx uses proprietary taste receptor-based assays, screening technologies and optimization chemistry to discover and develop novel flavors, flavor enhancers and taste modulators for the packaged food and beverage industry. Senomyx's current programs focus on the development of flavors, flavor enhancers and taste modulators in the savory, sweet, salt and bitter taste areas.
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